List of I.P for sale
Intellectual property
Domestic or overseas | Domestic | Form of the I.P | Patent |
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Patent no. | US 12/605672 | Registration no. | 8030466 |
Patent no. | EU 09173977.1 | Registration no. | 2305835 |
Name of the invention | 3′-o-fluorescently modified nucleotides and uses thereof | ||
Name of the invention(English) | |||
I.P sector | Others | ||
Image file[C] | |||
Attached file | |||
Patent evaluation rating | Patent evaluation score | ||
Technology valuation |
Commercialization information
I.P Abstract & Summary | The present invention relates to a DNA sequencing method using a nucleoside triphosphate with a fluorescent blocking group on its 32-OH end as a reversible terminator. Further, the present invention relates to sequencing-by-synthesis method using the mono-modified reversible terminator (MRT), the novel nucleotide monomer having a reversible fluorescent blocking group removable chemically or enzymatically at its 32-OH end. The sequencing method of the present invention facilitates sequencing of bases inserted by terminating extension of a nucleotide chain by the nucleotide monomer and then detecting fluorescence signal from 32-OH end. At this time, after analyzing the fluorescence signal, the blocking group conjugated to the 32-OH end can be effectively removed, indicating that a free 32-OH functional group can be successfully restored, so that the next monomer insertion is possible, making continuous sequencing possible. |
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Trade type of the I.P | Rights transfer ( Overall ) |
10,000,000KRW ~ 10,000,000KRW | |
I.P stage | Idea stage |
#Nucleotide, #Quinching, #Expansion, #Detect, #a fluorescent signal, #a monomer, #Restore, #Removal